Growth cone behavior and production of traction force.
نویسندگان
چکیده
منابع مشابه
Growth cone behavior and production of traction force
The growth cone must push its substrate rearward via some traction force in order to propel itself forward. To determine which growth cone behaviors produce traction force, we observed chick sensory growth cones under conditions in which force production was accommodated by movement of obstacles in the environment, namely, neurites of other sensory neurons or glass fibers. The movements of thes...
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Tyrosine kinase activity is known to be important in neuronal growth cone guidance. However, underlying cellular mechanisms are largely unclear. Here, we report how Src family tyrosine kinase activity controls apCAM-mediated growth cone steering by regulating the transmission of traction forces through receptor-cytoskeletal linkages. Increased levels of tyrosine phosphorylation were detected at...
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Few structures within the nervous system have received more attention than the neuronal growth cone. Initially named by Ramon y Cajal (1890) who recognized its dynamics and importance in histological sections, the growth cone plays essential roles in the development, repair, and modification of neuronal circuitry. Growth cones have a diverse repertoire of behaviors (Fig. 1). These behaviors und...
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Throughout the process of development, billions of neuronal axons are responsible for navigating through the nervous system and synapsing onto their appropriate targets. To establish their individual paths, neurons are guided by a complex and dynamic map of biochemical, topographic, and mechanical signals. At the tip of each neurite lies the growth cone – a dynamic structure responsible for int...
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ترانسفورماتورهای قدرت از اجزای اصلی شبکه تامین انرژی الکتریکی می باشند که عملکرد قابل اطمینان ترانسفورماتورها یکی از فاکتورهای مهم و تعیین کننده در تامین انرژی الکتریکی محسوب می شود. در نتیجه بررسی و مانیتور عملکرد ترانسفورماتورها در شبکه و همچنین عیب یابی این ترانسفورماتورها غیرقابل اجتناب و ضروری می باشد. به طور کلی عایق های مایع در صنعت فشار قوی کاربردهای متفاوتی دارند که مهمترین وظیفه آنها...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1990
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.111.5.1949